Recent studies suggest that calcitonin gene-related peptide (CGRP) neurons in the parabrachial nucleus (PBN) represent aversive information and signal a general alarm to the forebrain. If CGRP neurons serve as a true general alarm. their activation would modulate both passive and active defensive behaviors depending on the magnitude and context of the threat. However. https://www.roneverhart.com/Pedaltrain-Classic-1-w-Soft-case/