Accurate identification of DNA polymorphisms using next-generation sequencing technology is challenging because of a high rate of sequencing error and incorrect mapping of reads to reference genomes. Currently available short read aligners and DNA variant callers suffer from these problems. We developed the Coval software to improve the quality of short read alignments. https://mabelandfoxs.shop/product-category/cardigan/
Coval: improving alignment quality and variant calling accuracy for next-generation sequencing data.
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