Abstract Background Small-animal PET imaging is an important tool in preclinical oncology. This study evaluated the ability of a clinical SiPM-PET camera to image several rats simultaneously and to perform quantification data analysis. Methods Intrinsic spatial resolution was measured using 18F line sources. and image quality was assessed using a NEMA NU 4-2018 phantom. https://www.earthtoyes.shop/product-category/saxson/